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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24A All Species: 17.27
Human Site: S314 Identified Species: 29.23
UniProt: O95486 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95486 NP_068817.1 1093 119749 S314 A T G V P P S S L N Y P S G P
Chimpanzee Pan troglodytes XP_527165 1093 119711 S314 A T G V S P S S L N Y P S G P
Rhesus Macaque Macaca mulatta XP_001109620 1093 119674 S314 A T G V P P S S L N Y P S G P
Dog Lupus familis XP_850736 1100 120445 S321 T T G M P P S S L N Y S S G P
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 L312 A G M P P P S L S Y P S G P Q
Rat Rattus norvegicus NP_001099250 1089 118849 L311 A G M P P S S L N Y P S G P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510651 1234 134485 S420 A P G M S S T S L Q Y P S G P
Chicken Gallus gallus XP_414630 1100 120006 A321 A P G M Q A S A L Q Y P D G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 P314 P T A Q I P P P S A G Q F H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632 E115 C R N V L P I E K V E S P K I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 L448 Q P A V Y L F L L D V S F S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 S307 D G D V E P N S F A E M Y P M
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 K198 K N S S L L K K S K L P F G L
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 P222 S P D A N C A P K Y V R S T L
Conservation
Percent
Protein Identity: 100 99.4 97.7 92.1 N.A. 88.3 88.2 N.A. 69.1 74 N.A. 59.5 N.A. N.A. 44.7 N.A. 28.7
Protein Similarity: 100 99.8 98.2 94.2 N.A. 92.4 92 N.A. 76.2 83 N.A. 71.4 N.A. N.A. 59.4 N.A. 43
P-Site Identity: 100 93.3 100 80 N.A. 26.6 20 N.A. 60 46.6 N.A. 20 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 93.3 100 86.6 N.A. 26.6 20 N.A. 73.3 60 N.A. 20 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 34.5 29.7 31.7
Protein Similarity: N.A. N.A. N.A. 53.5 48.2 49.7
P-Site Identity: N.A. N.A. N.A. 20 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 15 8 0 8 8 8 0 15 0 0 0 0 8 % A
% Cys: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 15 0 0 0 0 0 0 8 0 0 8 0 0 % D
% Glu: 0 0 0 0 8 0 0 8 0 0 15 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 0 0 22 0 0 % F
% Gly: 0 22 43 0 0 0 0 0 0 0 8 0 15 50 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 8 % I
% Lys: 8 0 0 0 0 0 8 8 15 8 0 0 0 8 0 % K
% Leu: 0 0 0 0 15 15 0 22 50 0 8 0 0 0 15 % L
% Met: 0 0 15 22 0 0 0 0 0 0 0 8 0 0 8 % M
% Asn: 0 8 8 0 8 0 8 0 8 29 0 0 0 0 0 % N
% Pro: 8 29 0 15 36 58 8 15 0 0 15 43 8 22 43 % P
% Gln: 8 0 0 8 8 0 0 0 0 15 0 8 0 0 15 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % R
% Ser: 8 0 8 8 15 15 50 43 22 0 0 36 43 8 8 % S
% Thr: 8 36 0 0 0 0 8 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 43 0 0 0 0 0 8 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 22 43 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _